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Welcome to the ODO Website

The Opioid Drug Ontology (ODO) is a manually curated database that features assay-specific bioactivity data at opioid receptors, sourced from primary publications and online databases. It is implemented as a structured SQL relational database, designed to integrate and analyze relationships among bioassay entities, including compounds, assays, assay formats, cell lines, tissues, and organisms.

ODO Data Category Statistics

Activities37.4kCompounds13.4kAssays68Cell Lines65Tissues20Proteins12Documents1045AssayFormats4

Category

Activities
Compounds
Assays
Cell Lines
Tissues
Proteins
Documents
Assay Formats

About Us

The Opioid Drug Ontology Data Portal (ODO-DP) is a publicly accessible, ontology-driven resource that applies FAIR principles to opioid bioassay data. The portal currently integrates >37,000 curated bioactivity data points across compounds, assays, and targets, using standardized metadata and ontology-linked annotations to improve interoperability and reuse.

Data were curated primarily from ChEMBL and the scientific literature, with expert review and automated QC to ensure accurate assay annotations, target mapping, and compound structures.

What you can do:

Search, filter, and download data by assay format (biochemical, cell-based, tissue-based, organism-based) and explore curated metadata such as endpoint values, experimental conditions, and compound properties.

🔍 Filtering instructions: see "UI Search and Filtering" in our GitHub README.

📘 Project repository: OpioidDrugOntology.github.io

🧬 Development Team

Nicolette C. Ross

Primary Curator, Project Design, Development

Kathleen M. Jagodnik

Project Development

Lukas Rupprecht

Data Architecture

Ritik Bhandari

Data Architecture

Alon Bartal

Conceptualization, Project Development

Stephan C. Schürer

Conceptualization, Project Development

Affiliation and Acknowledgements

🏛️ Institutional Affiliation

Department of Molecular and Cellular Pharmacology
University of Miami Miller School of Medicine

Miami, FL, USA

🎓 Funding & Acknowledgments

Supported by NIH grants R21DA048313, U01LM012630, and R01LM013391

📫 Contact

Schürer Lab: schurerlab.org

Email: sschurer@med.miami.edu